Overview

  • Product name
  • Description
    Mouse polyclonal to MMP10
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human MMP10 protein (NP_002416.1).

  • Positive control
    • Human pancreas tissue lysate; A431 cell lysate; MMP10 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab89638 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa.

Target

  • Function
    Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
  • Sequence similarities
    Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
  • Domain
    The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Matrix metallopeptidase 10 (stromelysin 2) antibody
    • Matrix metalloprotease 10 antibody
    • Matrix metalloproteinase 10 (stromelysin 2) antibody
    • Matrix metalloproteinase 10 antibody
    • Matrix metalloproteinase-10 antibody
    • MMP 10 antibody
    • MMP-10 antibody
    • Mmp10 antibody
    • MMP10_HUMAN antibody
    • SL 2 antibody
    • SL-2 antibody
    • SL2 antibody
    • STMY 2 antibody
    • STMY2 antibody
    • Stromelysin 2 antibody
    • Stromelysin II antibody
    • Stromelysin-2 antibody
    • Stromelysin2 antibody
    • StromelysinII antibody
    • Transin 2 antibody
    • Transin-2 antibody
    • Transin2 antibody
    see all

Images

  • Anti-MMP10 antibody (ab89638) at 1 µg/ml + human pancreas tissue lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 54 kDa
    Observed band size : ~50 kDa (why is the actual band size different from the predicted?)
  • Anti-MMP10 antibody (ab89638) at 1 µg/ml + A431 cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 54 kDa
    Observed band size : ~60 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-MMP10 antibody (ab89638) at 1 µg/ml

    Lane 1 : MMP10 transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 54 kDa
    Observed band size : 54 kDa

References

ab89638 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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