Overview

  • Product name
    Anti-MMP15 antibody, prediluted
    See all MMP15 primary antibodies
  • Description
    Rabbit polyclonal to MMP15, prediluted
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A synthetic peptide from the catalytic domain of mouse MMP15 protein.

  • Positive control
    • Placenta.

Properties

Applications

Our Abpromise guarantee covers the use of ab15476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Ready diluted for 10 min at RT. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.
    • Tissue specificity
      Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.
    • Sequence similarities
      Belongs to the peptidase M10A family.
      Contains 4 hemopexin-like domains.
    • Domain
      The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • Post-translational
      modifications
      The precursor is cleaved by a furin endopeptidase.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AI503551 antibody
      • Matrix metallopeptidase 15 membrane inserted antibody
      • Matrix metalloproteinase 15 antibody
      • Matrix metalloproteinase-15 antibody
      • Membrane type 2 matrix metalloproteinase antibody
      • Membrane type matrix metalloproteinase 2 antibody
      • Membrane-type matrix metalloproteinase 2 antibody
      • Membrane-type-2 matrix metalloproteinase antibody
      • MMP 15 antibody
      • MMP-15 antibody
      • MMP15 antibody
      • MMP15_HUMAN antibody
      • MT MMP 2 antibody
      • MT-MMP 2 antibody
      • MT2 MMP antibody
      • MT2-MMP antibody
      • MT2MMP antibody
      • MTMMP 2 antibody
      • MTMMP2 antibody
      • SMCP 2 antibody
      • SMCP-2 antibody
      • SMCP2 antibody
      see all

    Images

    • ab15476 staining MMP15 in human placenta by Immunocytochemistry (FFPE-sections).

    References

    ab15476 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab15476.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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