Overview

  • Product name
  • Description
    Rabbit polyclonal to MMP23
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 92-362 of Human MMP23 (Uniprot: O75900)

  • Positive control
    • 293T; A431 or Raji cell lysates, Cal27 xenograft
  • General notes
    Keep as a concentrated solution

Properties

Applications

Our Abpromise guarantee covers the use of ab155416 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 44 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Suggested antigen retrieval using heat mediated 10mM citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).

Target

  • Function
    Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
  • Tissue specificity
    Predominantly expressed in ovary, testis and prostate.
  • Sequence similarities
    Belongs to the peptidase M10A family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • Domain
    The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
  • Post-translational
    modifications
    N-glycosylated.
    Proteolytic cleavage might yield an active form.
  • Cellular localization
    Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
  • Information by UniProt
  • Database links
  • Alternative names
    • Femalysin antibody
    • Matrix metallopeptidase 21 antibody
    • Matrix metallopeptidase 23A (pseudogene) antibody
    • Matrix metallopeptidase 23A antibody
    • Matrix metallopeptidase 23B antibody
    • Matrix metalloproteinase 22 antibody
    • Matrix metalloproteinase 23 antibody
    • Matrix metalloproteinase 23B antibody
    • Matrix metalloproteinase in the female reproductive tract antibody
    • Matrix metalloproteinase-21 antibody
    • Matrix metalloproteinase-22 antibody
    • Matrix metalloproteinase-23 antibody
    • MIFR antibody
    • MIFR-1 antibody
    • MIFR1 antibody
    • MMP 23 antibody
    • MMP-21 antibody
    • MMP-22 antibody
    • MMP-23 antibody
    • MMP21 antibody
    • MMP22 antibody
    • MMP23_HUMAN antibody
    • MMP23A antibody
    • MMP23B antibody
    • soluble form antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Cal27 xenograft, labeling MMP23 with ab155416 at 1/500.
  • Anti-MMP23 antibody (ab155416) at 1/5000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size: 44 kDa



    10% SDS PAGE

References

ab155416 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab155416.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up