Overview

  • Product nameAnti-MMP23 antibody
    See all MMP23 primary antibodies
  • Description
    Rabbit polyclonal to MMP23
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide derived from human MMP23.

  • Positive control
    • SKOV3 cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab53148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).
ELISA 1/10000.

Target

  • FunctionProtease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
  • Tissue specificityPredominantly expressed in ovary, testis and prostate.
  • Sequence similaritiesBelongs to the peptidase M10A family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • DomainThe toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
  • Post-translational
    modifications
    N-glycosylated.
    Proteolytic cleavage might yield an active form.
  • Cellular localizationEndoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
  • Information by UniProt
  • Database links
  • Alternative names
    • Femalysin antibody
    • Matrix metallopeptidase 21 antibody
    • Matrix metallopeptidase 23A (pseudogene) antibody
    • Matrix metallopeptidase 23A antibody
    • Matrix metallopeptidase 23B antibody
    • Matrix metalloproteinase 22 antibody
    • Matrix metalloproteinase 23 antibody
    • Matrix metalloproteinase 23B antibody
    • Matrix metalloproteinase in the female reproductive tract antibody
    • Matrix metalloproteinase-21 antibody
    • Matrix metalloproteinase-22 antibody
    • Matrix metalloproteinase-23 antibody
    • MIFR antibody
    • MIFR-1 antibody
    • MIFR1 antibody
    • MMP 23 antibody
    • MMP-21 antibody
    • MMP-22 antibody
    • MMP-23 antibody
    • MMP21 antibody
    • MMP22 antibody
    • MMP23_HUMAN antibody
    • MMP23A antibody
    • MMP23B antibody
    • soluble form antibody
    see all

Anti-MMP23 antibody images

  • All lanes : Anti-MMP23 antibody (ab53148) at 1/500 dilution

    Lane 1 : Extracts from SKOV3 cells
    Lane 2 : Extracts from SKOV3 cells with immunising peptide


    Predicted band size : 44 kDa
    Observed band size : 44 kDa

References for Anti-MMP23 antibody (ab53148)

This product has been referenced in:
  • Miller JP  et al. Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease. Neuron 67:199-212 (2010). WB ; Human . Read more (PubMed: 20670829) »

See 1 Publication for this product

Product Wall

The MMP23 antibody ab53148 was raised against a peptide within amino acids 360-390 which is a range located at the C terminus of the protein, accession O75900, http://www.uniprot.org/uniprot/O75900.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"