Overview

  • Product nameAnti-MMP23 antibody
    See all MMP23 primary antibodies
  • Description
    Rabbit polyclonal to MMP23
  • SpecificityMMP23 (Cleaved-Tyr79) antibody detects endogenous levels of fragment of activated MMP23 resulting from cleavage adjacent to Tyr79.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Pig, Chimpanzee, Zebrafish
  • Immunogen

    Synthetic peptide (Human)

  • Positive control
    • Extracts from 293 cells, treated with etoposide (25uM, 1hour).

Properties

Applications

Our Abpromise guarantee covers the use of ab72799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
ELISA 1/5000.

Target

  • FunctionProtease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
  • Tissue specificityPredominantly expressed in ovary, testis and prostate.
  • Sequence similaritiesBelongs to the peptidase M10A family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • DomainThe toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
  • Post-translational
    modifications
    N-glycosylated.
    Proteolytic cleavage might yield an active form.
  • Cellular localizationEndoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
  • Information by UniProt
  • Database links
  • Alternative names
    • Femalysin antibody
    • Matrix metallopeptidase 21 antibody
    • Matrix metallopeptidase 23A (pseudogene) antibody
    • Matrix metallopeptidase 23A antibody
    • Matrix metallopeptidase 23B antibody
    • Matrix metalloproteinase 22 antibody
    • Matrix metalloproteinase 23 antibody
    • Matrix metalloproteinase 23B antibody
    • Matrix metalloproteinase in the female reproductive tract antibody
    • Matrix metalloproteinase-21 antibody
    • Matrix metalloproteinase-22 antibody
    • Matrix metalloproteinase-23 antibody
    • MIFR antibody
    • MIFR-1 antibody
    • MIFR1 antibody
    • MMP 23 antibody
    • MMP-21 antibody
    • MMP-22 antibody
    • MMP-23 antibody
    • MMP21 antibody
    • MMP22 antibody
    • MMP23_HUMAN antibody
    • MMP23A antibody
    • MMP23B antibody
    • soluble form antibody
    see all

Anti-MMP23 antibody images

  • All lanes : Anti-MMP23 antibody (ab72799) at 1/1000 dilution

    Lane 1 : 293 cells
    Lane 2 : 293 cells with MMP23 (cleaved Tyr79) blocking peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 44 kDa

References for Anti-MMP23 antibody (ab72799)

ab72799 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"