Overview

  • Product nameAnti-MMP23 antibody
    See all MMP23 primary antibodies
  • Description
    Rabbit polyclonal to MMP23
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide derived from the C terminus of human MMP23 protein.

  • Positive control
    • Paraffin embedded Human placenta tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab74215 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/25 for 10 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProtease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
    • Tissue specificityPredominantly expressed in ovary, testis and prostate.
    • Sequence similaritiesBelongs to the peptidase M10A family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    • DomainThe toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
    • Post-translational
      modifications
      N-glycosylated.
      Proteolytic cleavage might yield an active form.
    • Cellular localizationEndoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
    • Information by UniProt
    • Database links
    • Alternative names
      • Femalysin antibody
      • Matrix metallopeptidase 21 antibody
      • Matrix metallopeptidase 23A (pseudogene) antibody
      • Matrix metallopeptidase 23A antibody
      • Matrix metallopeptidase 23B antibody
      • Matrix metalloproteinase 22 antibody
      • Matrix metalloproteinase 23 antibody
      • Matrix metalloproteinase 23B antibody
      • Matrix metalloproteinase in the female reproductive tract antibody
      • Matrix metalloproteinase-21 antibody
      • Matrix metalloproteinase-22 antibody
      • Matrix metalloproteinase-23 antibody
      • MIFR antibody
      • MIFR-1 antibody
      • MIFR1 antibody
      • MMP 23 antibody
      • MMP-21 antibody
      • MMP-22 antibody
      • MMP-23 antibody
      • MMP21 antibody
      • MMP22 antibody
      • MMP23_HUMAN antibody
      • MMP23A antibody
      • MMP23B antibody
      • soluble form antibody
      see all

    Anti-MMP23 antibody images

    • ab74215 at 1/25 dilution staining MMP23 in human placenta by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    References for Anti-MMP23 antibody (ab74215)

    ab74215 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"