Overview

  • Product name
  • Description
    Rabbit polyclonal to MMP23
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide derived from the C terminus of human MMP23 protein.

  • Positive control
    • Paraffin embedded Human placenta tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab74215 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/25 for 10 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
    • Tissue specificity
      Predominantly expressed in ovary, testis and prostate.
    • Sequence similarities
      Belongs to the peptidase M10A family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    • Domain
      The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
    • Post-translational
      modifications
      N-glycosylated.
      Proteolytic cleavage might yield an active form.
    • Cellular localization
      Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
    • Information by UniProt
    • Database links
    • Alternative names
      • Femalysin antibody
      • Matrix metallopeptidase 21 antibody
      • Matrix metallopeptidase 23A (pseudogene) antibody
      • Matrix metallopeptidase 23A antibody
      • Matrix metallopeptidase 23B antibody
      • Matrix metalloproteinase 22 antibody
      • Matrix metalloproteinase 23 antibody
      • Matrix metalloproteinase 23B antibody
      • Matrix metalloproteinase in the female reproductive tract antibody
      • Matrix metalloproteinase-21 antibody
      • Matrix metalloproteinase-22 antibody
      • Matrix metalloproteinase-23 antibody
      • MIFR antibody
      • MIFR-1 antibody
      • MIFR1 antibody
      • MMP 23 antibody
      • MMP-21 antibody
      • MMP-22 antibody
      • MMP-23 antibody
      • MMP21 antibody
      • MMP22 antibody
      • MMP23_HUMAN antibody
      • MMP23A antibody
      • MMP23B antibody
      • soluble form antibody
      see all

    Images

    • ab74215 at 1/25 dilution staining MMP23 in human placenta by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    References

    ab74215 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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