Overview

  • Product nameAnti-MMP25 antibody - C-terminal
    See all MMP25 primary antibodies
  • Description
    Rabbit polyclonal to MMP25 - C-terminal
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide from the C terminal region of human MMP25 conjugated to KLH

  • Positive control
    • Mouse liver tissue and HL60 cell lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab70881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).

Target

  • FunctionMay activate progelatinase A.
  • Tissue specificityExpressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas.
  • Sequence similaritiesBelongs to the peptidase M10A family.
    Contains 4 hemopexin repeats.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Post-translational
    modifications
    The precursor is cleaved by a furin endopeptidase.
  • Cellular localizationCell membrane. Secreted, extracellular space, extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Leukolysin antibody
    • matrix metallopeptidase 25 antibody
    • matrix metallopeptidase like 1 antibody
    • matrix metalloproteinase 20 antibody
    • Matrix Metalloproteinase 25 antibody
    • Matrix metalloproteinase 25 precursor antibody
    • Matrix metalloproteinase-25 antibody
    • Membrane type 6 Matrix Metalloproteinase antibody
    • Membrane type Matrix Metalloproteinase 6 antibody
    • Membrane-type matrix metalloproteinase 6 antibody
    • Membrane-type-6 matrix metalloproteinase antibody
    • MMP 25 antibody
    • MMP-25 antibody
    • MMP20 antibody
    • MMP20A antibody
    • MMP25 antibody
    • MMP25_HUMAN antibody
    • MMPL1 antibody
    • MT-MMP 6 antibody
    • MT6-MMP antibody
    • MT6MMP antibody
    • MTMMP6 antibody
    see all

Anti-MMP25 antibody - C-terminal images

  • All lanes : Anti-MMP25 antibody - C-terminal (ab70881) at 1/100 dilution

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : HL60 cell lysate

    Lysates/proteins at 12.5 µg per lane.


    Predicted band size : 63 kDa
    Observed band size : 63 kDa

References for Anti-MMP25 antibody - C-terminal (ab70881)

ab70881 has not yet been referenced specifically in any publications.

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