Overview

  • Product nameAnti-MMP28 antibody
    See all MMP28 primary antibodies
  • Description
    Rabbit polyclonal to MMP28
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 194-223 of Human MMP28 (NP_001027449.1, NP_077278.1).

  • Positive control
    • MDA-MB435 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116580 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 59 kDa.

Target

  • FunctionCan degrade casein. Could play a role in tissues homeostasis and repair.
  • Tissue specificityExpressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytesis. Widely expressed in several carcinomas as well. Is up-regulated in response to injury in the skin.
  • Sequence similaritiesBelongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Post-translational
    modifications
    The precursor is cleaved by a furin endopeptidase.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Epilysin antibody
    • Matrix metalloproteinase 28 antibody
    • Matrix metalloproteinase-28 antibody
    • MM 28 antibody
    • MM28 antibody
    • MMP 25 antibody
    • MMP 28 antibody
    • MMP-28 antibody
    • MMP25 antibody
    • MMP28 antibody
    • MMP28_HUMAN antibody
    see all

Anti-MMP28 antibody images

  • Anti-MMP28 antibody (ab116580) at 1/100 dilution + MDA-MB435 cell line lysate at 35 µg

    Predicted band size : 59 kDa

References for Anti-MMP28 antibody (ab116580)

ab116580 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116580.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"