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Rabbit polyclonal to MMP3 - N-terminal
Synthetic peptide, corresponding to a region within N terminal amino acids 1-65 of Human MMP3.
293T and Raji whole cell lysates; A549 cells; Human salivary gland cancer tissue.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 0.75% Glycine, 1.21% Tris, 10% Glycerol
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 53 kDa.
1/100 - 1/1000.
1/100 - 1/1000.
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
Secreted > extracellular space > extracellular matrix.
Information by UniProt
Matrix metalloproteinase 3 antibody
Matrix metalloproteinase-3 antibody
Western blot - Anti-MMP3 antibody - N-terminal (ab137741)
All lanes : Anti-MMP3 antibody - N-terminal (ab137741) at 1/1000 dilution Lane 1 : 293T whole cell lysate Lane 2 : Raji whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size : 53 kDa
Immunocytochemistry/ Immunofluorescence - Anti-MMP3 antibody - N-terminal (ab137741)
Immunofluorescent analysis of paraformaldehyde-fixed A549 cells labelling MMP3 with ab137741 at 1/200 dilution. Lower image is merged with DNA probe.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MMP3 antibody (ab137741)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Salivary gland cancer tissue labelling MMP3 with ab137741 at 1/100 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"