MMP3 Inhibitor Screening Assay Kit (Fluorometric) (ab139440)

Overview

  • Product name
    MMP3 Inhibitor Screening Assay Kit (Fluorometric)
    See all MMP3 kits
  • Assay type
    Enzyme activity
  • Product overview

    Abcam MMP3 Inhibitor Screening Assay Kit (Fluorometric) (ab139440)  is a complete assay system designed to screen MMP3 inhibitors using a quenched fluorogenic peptide: MMP Fluorogenic Substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 [Mca=(7-methoxycoumarin-4-yl)-acetyl; Dpa=N-3-(2,4-dinitrophenyl)-L-α-β-diaminopropionyl]. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP3, a potential therapeutic target. The compound NNGH is also included as a prototypic control inhibitor.

  • Tested applications
    Suitable for: Functional Studiesmore details

Properties

Applications

Our Abpromise guarantee covers the use of ab139440 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.

Images

Protocols

References

ab139440 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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