Overview

  • Product nameAnti-MMP7 antibody
    See all MMP7 primary antibodies
  • Description
    Goat polyclonal to MMP7
  • Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    QKLYGKRSNSRKK

    conjugated to KLH, corresponding to C terminal amino acids 255-267 of Human MMP7.

  • Positive control
    • Human uterus tissue; Human breast lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab112017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 30 kDa.
IHC-P Use a concentration of 3.75 µg/ml.
ELISA 1/64000.

Target

  • FunctionDegrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
  • Sequence similaritiesBelongs to the peptidase M10A family.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Matrilysin antibody
    • Matrin antibody
    • Matrix Metalloproteinase 7 antibody
    • Matrix metalloproteinase-7 antibody
    • MMP 7 antibody
    • MMP-7 antibody
    • MMP7 antibody
    • MMP7_HUMAN antibody
    • MPSL1 antibody
    • PUMP 1 antibody
    • Pump 1 protease antibody
    • Pump-1 protease antibody
    • PUMP1 antibody
    • Uterine matrilysin antibody
    • Uterine metalloproteinase antibody
    see all

Anti-MMP7 antibody images

  • Immunohistochemical analysis of MMP7 expression in formalin-fixed, paraffin-embedded Human uterus using ab112017 at 3.75 µg/ml.
  • Anti-MMP7 antibody (ab112017) at 0.03 µg/ml + Human breast lysate (in RIPA buffer) at 35 µg

    Predicted band size : 30 kDa

References for Anti-MMP7 antibody (ab112017)

ab112017 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"