Anti-MMP9 antibody [SB15c] (HRP) (ab46728)


  • Product nameAnti-MMP9 antibody [SB15c] (HRP)
    See all MMP9 primary antibodies
  • Description
    Mouse monoclonal [SB15c] to MMP9 (HRP)
  • ConjugationHRP
  • SpecificityAb46728 recognizes MMP9, but does not cross react with MMP1, MMP2 or MMP3.
  • Tested applicationsSuitable for: ICC, WB, ELISA, IHC-Fr, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human MMP9.


Our Abpromise guarantee covers the use of ab46728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 78 kDa. PubMed: 26998102
ELISA Use a concentration of 1 µg/ml.
IHC-Fr 1/1000 - 1/2000.
IHC-P Use at an assay dependent concentration.


  • FunctionMay play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-
    -Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
  • Tissue specificityProduced by normal alveolar macrophages and granulocytes.
  • Involvement in diseaseIntervertebral disc disease
    Metaphyseal anadysplasia 2
  • Sequence similaritiesBelongs to the peptidase M10A family.
    Contains 3 fibronectin type-II domains.
    Contains 4 hemopexin repeats.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Post-translational
    Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9.
    N- and O-glycosylated.
  • Cellular localizationSecreted, extracellular space, extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 82 kDa matrix metalloproteinase-9 antibody
    • 92 kDa gelatinase antibody
    • 92 kDa type IV collagenase antibody
    • CLG 4B antibody
    • CLG4B antibody
    • Collagenase Type 4 beta antibody
    • Collagenase type IV 92 KD antibody
    • EC antibody
    • Gelatinase 92 KD antibody
    • Gelatinase B antibody
    • Gelatinase beta antibody
    • GelatinaseB antibody
    • GELB antibody
    • Macrophage gelatinase antibody
    • MANDP2 antibody
    • Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) antibody
    • Matrix Metalloproteinase 9 antibody
    • MMP 9 antibody
    • MMP-9 antibody
    • MMP9 antibody
    • MMP9_HUMAN antibody
    • Type V collagenase antibody
    see all

Anti-MMP9 antibody [SB15c] (HRP) images

  • Immunohistochemical analysis of paraffin embedded Human gastric cancer tissue labeling MMP9 with ab46728 at 1/1000 dilution

    Left:Mouse IgG-HRP isotype control

    Right:Sample MMP9 antibody

References for Anti-MMP9 antibody [SB15c] (HRP) (ab46728)

ab46728 has not yet been referenced specifically in any publications.

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Thank you for your enquiry. Unfortunately, we have not tested this product to determine if it will also recognize the precursor to MMP-9 or not.