Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab13906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 17 kDa).

Target

  • Function
    Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
  • Tissue specificity
    Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues.
  • Sequence similarities
    Belongs to the ubiquitin-conjugating enzyme family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1 alpha 25 dihydroxyvitamin D3 inducible antibody
    • DDVit 1 antibody
    • DDVIT1 antibody
    • EDAF-1 antibody
    • EDAF1 antibody
    • EDPF-1 antibody
    • EDPF1 antibody
    • Enterocyte differentiation associated factor EDAF 1 antibody
    • Enterocyte differentiation promoting factor antibody
    • Enterocyte differentiation-associated factor 1 antibody
    • Enterocyte differentiation-promoting factor 1 antibody
    • Methyl methanesulfonate sensitive 2 antibody
    • MMS 2 antibody
    • MMS2 antibody
    • MMS2 homolog antibody
    • UB2V2_HUMAN antibody
    • UBE2V 2 antibody
    • UBE2V2 antibody
    • Ubiquitin conjugating enzyme E2 variant 2 antibody
    • Ubiquitin conjugating enzyme E2v2 antibody
    • Ubiquitin-conjugating enzyme E2 variant 2 antibody
    • UEV 2 antibody
    • UEV2 antibody
    • Vitamin D3 inducible protein antibody
    • Vitamin D3-inducible protein antibody
    see all

Images



  • Predicted band size : 17 kDa


    Detection of UEV2 in HL-60 cell lysate with ab13906 at 2ug/ml dilution.

References

This product has been referenced in:
  • Fernández-Medarde A  et al. Laser microdissection and microarray analysis of the hippocampus of Ras-GRF1 knockout mice reveals gene expression changes affecting signal transduction pathways related to memory and learning. Neuroscience 146:272-85 (2007). IHC-P ; Mouse . Read more (PubMed: 17321057) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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