Overview

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab101888 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 155 kDa (predicted molecular weight: 142 kDa).

Target

  • FunctionComponent of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA.
  • Sequence similaritiesBelongs to the MMS22 family. MMS22L subfamily.
  • Cellular localizationNucleus. Localizes to DNA damage sites, accumulates at stressed replication forks.
  • Target information above from: UniProt accession Q6ZRQ5 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • C6orf167 antibody
    • C6orf167 chromosome 6 open reading frame 167 antibody
    • chromosome 6 open reading frame 167 antibody
    • dJ39B17.2 antibody
    • DKFZp686C20164 antibody
    • DKFZp781C2113 antibody
    • FLJ46180 antibody
    • homologous to yeast Mms22 antibody
    • KIAA1900 antibody
    • Methyl methanesulfonate-sensitivity protein 22-like antibody
    • MMS22 like, DNA repair protein antibody
    • Mms22-like protein antibody
    • MMS22_HUMAN antibody
    • MMS22L antibody
    • OTTHUMP00000221009 antibody
    • Protein MMS22-like antibody
    • Uncharacterized protein C6orf167 antibody
    see all

Anti-MMS22L (C6ORF167) antibody images

  • Anti-MMS22L (C6ORF167) antibody (ab101888) at 1 µg/ml + Liver (Human) Tissue Lysate - adult normal tissue (ab29889) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 142 kDa
    Observed band size : 155 kDa (why is the actual band size different from the predicted?)


    Exposure time : 3 minutes

References for Anti-MMS22L (C6ORF167) antibody (ab101888)

ab101888 has not yet been referenced specifically in any publications.

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