Overview

  • Product nameAnti-MNDA antibody
    See all MNDA primary antibodies
  • Description
    Mouse polyclonal to MNDA
  • SpecificityAntibody reactive against mammalian transfected lysate.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-407 of Human MNDA

  • Positive control
    • Transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67641 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).

Target

  • FunctionMay act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
  • Tissue specificityExpressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia.
  • Sequence similaritiesContains 1 DAPIN domain.
    Contains 1 HIN-200 domain.
  • DomainIts N-terminal half (200 amino acids) is sufficient for maximum enhancement of YY1 DNA binding and a portion of this sequence is responsible for binding YY1.
  • Cellular localizationNucleus. Cytoplasm. Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.
  • Information by UniProt
  • Database links
  • Alternative names
    • MNDA antibody
    • MNDA_HUMAN antibody
    • Myeloid cell nuclear differentiation antigen antibody
    • OTTHUMP00000024384 antibody
    • PYHIN3 antibody
    see all

Anti-MNDA antibody images

  • All lanes : Anti-MNDA antibody (ab67641) at 1/500 dilution

    Lane 1 : MNDA trabsfected 293T cell lysate
    Lane 2 : non trabsfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 46 kDa
    Observed band size : 46 kDa

References for Anti-MNDA antibody (ab67641)

ab67641 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab67641.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"