Overview

  • Product nameAnti-MNDA antibody
    See all MNDA primary antibodies
  • Description
    Rabbit polyclonal to MNDA
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human)

  • Positive control
    • Transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab80265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/1562500.

WB Use a concentration of 1 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
  • Tissue specificityExpressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia.
  • Sequence similaritiesContains 1 DAPIN domain.
    Contains 1 HIN-200 domain.
  • DomainIts N-terminal half (200 amino acids) is sufficient for maximum enhancement of YY1 DNA binding and a portion of this sequence is responsible for binding YY1.
  • Cellular localizationNucleus. Cytoplasm. Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.
  • Information by UniProt
  • Database links
  • Alternative names
    • MNDA antibody
    • MNDA_HUMAN antibody
    • Myeloid cell nuclear differentiation antigen antibody
    • OTTHUMP00000024384 antibody
    • PYHIN3 antibody
    see all

Anti-MNDA antibody images

  • Anti-MNDA antibody (ab80265) at 1 µg/ml + transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 46 kDa
    Observed band size : 46 kDa

References for Anti-MNDA antibody (ab80265)

ab80265 has not yet been referenced specifically in any publications.

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