• Product nameAnti-MOB4A antibody
    See all MOB4A primary antibodies
  • Description
    Rabbit polyclonal to MOB4A
  • Specificityab72757 detects endogenous levels of total MOB4A protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide from an internal region of human MOB4A

  • Positive control
    • Extracts from 293, Cos7 and HUVEC cell extracts treated with IFN (2500U/ml, 30mins).


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
    Note: Without Mg2+ and Ca2+
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesAffinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab72757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).
ELISA 1/40000.


  • FunctionActivator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.
  • Tissue specificityAdrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver.
  • Sequence similaritiesBelongs to the MOB1/phocein family.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • MATS 2 antibody
    • MATS2 antibody
    • MGC33910 antibody
    • Mob 1A antibody
    • Mob 1B antibody
    • MOB 4A antibody
    • MOB kinase activator 1B antibody
    • Mob1 homolog 1A antibody
    • MOB1 Mps One Binder homolog B antibody
    • MOB1 Mps one binder kinase activator like 1A antibody
    • Mob1A antibody
    • Mob1B antibody
    • MOBKL 1A antibody
    • MOBKL1A antibody
    • MOL1A_HUMAN antibody
    • Mps one binder kinase activator like 1A antibody
    • Mps one binder kinase activator-like 1A antibody
    • Protein Mob4A antibody
    see all

Anti-MOB4A antibody images

  • All lanes : Anti-MOB4A antibody (ab72757) at 1/500 dilution

    Lane 1 : 293 cell extract treated with IFN (2500U/ml, 30mins)
    Lane 2 : Cos7 cell extract treated with IFN (2500U/ml, 30mins)
    Lane 3 : HUVEC extract treated with IFN (2500U/ml, 30mins)
    Lane 4 : 293 cell extract treated with IFN (2500U/ml, 30mins) with immunising peptide at 10 µg

    Lysates/proteins at 10 µg per lane.

    Predicted band size : 25 kDa
    Observed band size : 25 kDa
    Additional bands at : 85 kDa. We are unsure as to the identity of these extra bands.

References for Anti-MOB4A antibody (ab72757)

ab72757 has not yet been referenced specifically in any publications.

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