Overview

  • Product name
    Monensin sodium salt
  • Description
    Na+ ionophore
  • Biological description
    Na+ ionophore. Forms lipophilic complexes with monovalent cations to induce Na+ influx and H+/K+ efflux. Increases intracellular Ca2+ levels. Exhibits diverse biological actions; displays antibacterial properties and modulates ion gradients and intracellular pH. Apoptosis inducer.
  • Purity
    > 95%

Properties

References

This product has been referenced in:
  • Ketola K  et al. Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells. Mol Cancer Ther 9:3175-85 (2010). Read more (PubMed: 21159605) »
  • Mollenhauer HH  et al. Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity. Biochim Biophys Acta 1031:225-46 (1990). Read more (PubMed: 2160275) »
  • Singh M  et al. Effect of monensin, a Na+-specific carboxylic ionophore on the oxidative defense system in rat testis. Pharmacol Rep 59:456-61 (0). Read more (PubMed: 17901575) »

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