Anti-Monocarboxylic acid transporter 1 antibody (ab93048)

Overview

  • Product name
    Anti-Monocarboxylic acid transporter 1 antibody
    See all Monocarboxylic acid transporter 1 primary antibodies
  • Description
    Rabbit polyclonal to Monocarboxylic acid transporter 1
  • Tested applications
    Suitable for: WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat
  • Immunogen

    A synthetic peptide corresponding to N terminal residues of Mouse Monocarboxylic acid transporter 1

Properties

Applications

Our Abpromise guarantee covers the use of ab93048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA 1/2000 - 1/5000.
ICC/IF Use at an assay dependent concentration.

Target

  • Function
    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
  • Tissue specificity
    Widely expressed in normal and in cancer cells.
  • Involvement in disease
    Symptomatic deficiency in lactate transport
    Familial hyperinsulinemic hypoglycemia 7
  • Sequence similarities
    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ36745 antibody
    • HHF7 antibody
    • MCT 1 antibody
    • MCT antibody
    • MGC44475 antibody
    • Monocarboxylate transporter 1 antibody
    • Monocarboxylate transporter antibody
    • Monocarboxylate transporter isoform 1 antibody
    • Monocarboxylic acid transporter 1 antibody
    • MOT1_HUMAN antibody
    • Slc16a1 antibody
    • SLC16A1 protein antibody
    • Solute carrier family 16 (monocarboxylic acid transporters) member 1 antibody
    • Solute carrier family 16 member 1 (monocarboxylic acid transporter 1) antibody
    • Solute carrier family 16 member 1 antibody
    see all

References

ab93048 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Filter by Application

Filter by Species

Filter by Ratings

Application
Western blot
Sample
Chicken Tissue lysate - whole (Breast)
Gel Running Conditions
Reduced Denaturing
Loading amount
10 µg
Specification
Breast
Blocking step
Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5µg/mL · Temperature: 23°C
Username

Abcam user community

Verified customer

Submitted Jun 19 2017

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Rat Tissue sections (brain)
Antigen retrieval step
Other
Permeabilization
Yes - tween 20
Specification
brain
Blocking step
Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative
Formaldehyde
Username

Abcam user community

Verified customer

Submitted Oct 05 2015

Application
Immunocytochemistry/ Immunofluorescence
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 37°C
Sample
Rat Cell (astrocytes)
Specification
astrocytes
Permeabilization
No
Fixative
Paraformaldehyde
Username

Abcam user community

Verified customer

Submitted Nov 27 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up