Anti-Monocarboxylic acid transporter 1 antibody (ab98868)

Overview

  • Product name
    Anti-Monocarboxylic acid transporter 1 antibody
    See all Monocarboxylic acid transporter 1 primary antibodies
  • Description
    Rabbit polyclonal to Monocarboxylic acid transporter 1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cat
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 215-264 (EKAGKSGVKK DLHDANTDLI GRHPKQEKRS VFQTINQFLD LTLFTHRGFL) of Human Monocarboxylic acid transporter 1 (NP_003042)

  • Positive control
    • HT1080 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P 1/100.

Target

  • Function
    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
  • Tissue specificity
    Widely expressed in normal and in cancer cells.
  • Involvement in disease
    Symptomatic deficiency in lactate transport
    Familial hyperinsulinemic hypoglycemia 7
  • Sequence similarities
    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ36745 antibody
    • HHF7 antibody
    • MCT 1 antibody
    • MCT antibody
    • MGC44475 antibody
    • Monocarboxylate transporter 1 antibody
    • Monocarboxylate transporter antibody
    • Monocarboxylate transporter isoform 1 antibody
    • Monocarboxylic acid transporter 1 antibody
    • MOT1_HUMAN antibody
    • Slc16a1 antibody
    • SLC16A1 protein antibody
    • Solute carrier family 16 (monocarboxylic acid transporters) member 1 antibody
    • Solute carrier family 16 member 1 (monocarboxylic acid transporter 1) antibody
    • Solute carrier family 16 member 1 antibody
    see all

Anti-Monocarboxylic acid transporter 1 antibody images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human bronchial epithelial tissue labelling Monocarboxylic acid transporter 1 with ab98868 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the membrane and cytoplasm. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - Monocarboxylic acid transporter 1. Right - Merge.
  • Anti-Monocarboxylic acid transporter 1 antibody (ab98868) at 1 µg/ml + HT1080 cell lysate at 10 µg

    Predicted band size : 54 kDa
    Gel concentration: 12%

References for Anti-Monocarboxylic acid transporter 1 antibody (ab98868)

ab98868 has not yet been referenced specifically in any publications.

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The anti-Monocarboxylic acid transporter 1 antibody (ab98868) has been raised againsta synthetic peptide taken from the region 215-264 of the humanMonocarboxylic acid transporter 1 (SwissProt reference P53985). Th...

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