Anti-Monocyte + Macrophage antibody [KUL01] (ab25403)

Overview

  • Product nameAnti-Monocyte + Macrophage antibody [KUL01]
    See all Monocyte + Macrophage primary antibodies
  • Description
    Mouse monoclonal [KUL01] to Monocyte + Macrophage
  • SpecificityThis antibody recognises monocytes and macrophages as well as interdigitating cells and activated microglia cells. The antibody does not react with B (Bu1 positive) or T (CD3 positive) lymphocytes.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Chicken
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes


    This antibody is useful in the study of the development, distribution, function and ontogeny of the mononuclear phagocyte system (MPS) of the chicken by exclusively recognizing the cells of the MPS.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 8.20
    Constituent: 100% Borate buffered saline
  • Concentration information loading...
  • PurityIgG fraction
  • Primary antibody notesThis antibody is useful in the study of the development, distribution, function and ontogeny of the mononuclear phagocyte system (MPS) of the chicken by exclusively recognizing the cells of the MPS.
  • ClonalityMonoclonal
  • Clone numberKUL01
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab25403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • RelevanceMonocyte and macrophage are white blood cells that roam the body tissues engulfing foreign organisms. A monocyte is a leukocyte, part of the human body's immune system that protects against blood-borne pathogens and moves quickly (aprox. 8-12 hours) to sites of infection in the tissues. Monocytes are usually identified in stained smears by their large bi-lobed nucleus. Macrophages are cells within the tissues that originate from specific white blood cells called monocytes. Monocytes and macrophages are phagocytes, acting in both nonspecific defense (or innate immunity) as well as specific defense (or cell-mediated immunity) of vertebrate animals. Their role is to phagocytize (engulf and then digest) cellular debris and pathogens either as stationary or mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen.
  • Alternative names
    • Macrophages antibody
    • Monocytes antibody

References for Anti-Monocyte + Macrophage antibody [KUL01] (ab25403)

This product has been referenced in:
  • Mast J  et al. Characterisation of chicken monocytes, macrophages and interdigitating cells by the monoclonal antibody KUL01. Vet Immunol Immunopathol 61:343-57 (1998). Read more (PubMed: 9613446) »

See 1 Publication for this product

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