Recombinant
RabMAb

Anti-MORC3 antibody [EPR10113(B)] (ab150398)

Overview

  • Product name
    Anti-MORC3 antibody [EPR10113(B)]
    See all MORC3 primary antibodies
  • Description
    Rabbit monoclonal [EPR10113(B)] to MORC3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (C terminal)

  • Positive control
    • Human skeletal muscle and fetal heart lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab150398 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 107 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233).
    • Tissue specificity
      Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney.
    • Sequence similarities
      Contains 1 CW-type zinc finger.
    • Post-translational
      modifications
      Sumoylation is involved in interaction with PML and localization to PML nuclear bodies.
    • Cellular localization
      Nucleus, nucleoplasm. Nucleus matrix. Nucleus, PML body. Also found in PML-independent nuclear bodies. Localization to nuclear bodies is ATP-dependent.
    • Information by UniProt
    • Database links
    • Alternative names
      • KIAA0136 antibody
      • Microrchidia 3 antibody
      • MORC family CW type zinc finger 3 antibody
      • MORC family CW type zinc finger protein 3 antibody
      • MORC family CW-type zinc finger protein 3 antibody
      • MORC3 antibody
      • MORC3_HUMAN antibody
      • Nuclear matrix protein 2 antibody
      • Nuclear matrix protein NXP2 antibody
      • NXP2 antibody
      • ZCW5 antibody
      • ZCWCC3 antibody
      • Zinc finger CW type coiled coil domain 3 antibody
      • Zinc finger CW type coiled coil domain protein 3 antibody
      • Zinc finger CW type with coiled coil domain 3 antibody
      • Zinc finger CW-type coiled-coil domain protein 3 antibody
      see all

    Images

    • All lanes : Anti-MORC3 antibody [EPR10113(B)] (ab150398) at 1/1000 dilution

      Lane 1 : Human skeletal
      muscle lysate
      Lane 2 : Fetal heart lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 107 kDa

    References

    ab150398 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab150398.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up