The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceMorphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.
Morphine 6 antibody
Anti-Morphine antibody [3A6] images
ELISA - Morphine antibody [3A6] (ab23357)
A competitive ELISA was performed using various drugs at a concentration of 10 ng/ml. Only morphine was able to block the binding of ab23357 to the antigen.
1. Positive control.
References for Anti-Morphine antibody [3A6] (ab23357)
has not yet been referenced specifically in any publications.
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