Overview

  • Product nameAnti-Morphine antibody
    See all Morphine primary antibodies
  • Description
    Mouse monoclonal to Morphine
  • SpecificityThis antibody has a Kd of 2 nM for morphine and related alkaloids (e.g., codeine, nalorphine, andnaltrexone).
  • Tested applicationsSuitable for: ELISAmore details
  • Immunogen

    Morphine conjugated at the C6 position to bovine serum albumin.

Properties

Applications

Our Abpromise guarantee covers the use of ab1060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesDilute in PBS or medium which is identical to that used in the assay system.
    This antibody may be used inimmunoassays for detection of alkaloid/narcotic drugs
  • Target

    • RelevanceMorphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.
    • Alternative names
      • Morphine 6 antibody

    References for Anti-Morphine antibody (ab1060)

    ab1060 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"