Anti-Mortality Factor 4 like 2 antibody (ab49184)


  • Product name
    Anti-Mortality Factor 4 like 2 antibody
    See all Mortality Factor 4 like 2 primary antibodies
  • Description
    Rabbit polyclonal to Mortality Factor 4 like 2
  • Specificity
    This antibody recognizes Mortality Factor 4 like 2
  • Tested applications
    Suitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog, Chimpanzee
  • Immunogen

    A region within synthetic peptide: ASSGKKTAGP QQKNLEPALP GRWGGRSAEN PPSGSVRKTR KNKQKTPGNG, corresponding to N terminal amino acids 37-86 of Human Mortality Factor 4 like 2

  • Positive control
    • Human brain, fetal brain lysate.


Our Abpromise guarantee covers the use of ab49184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 µg/ml. Detects a band of approximately 32 kDa (predicted molecular weight: 32 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay was 1:1562500.


  • Function
    Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
  • Sequence similarities
    Belongs to the MRG family.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0026 antibody
    • MO4L2_HUMAN antibody
    • MORF related gene X protein antibody
    • MORF-related gene X protein antibody
    • Morf4l2 antibody
    • MORFL2 antibody
    • Mortality factor 4 like protein 2 antibody
    • Mortality factor 4-like protein 2 antibody
    • MRGX antibody
    • MSL3 2 protein antibody
    • Protein MSL3-2 antibody
    • Transcription factor like protein MRGX antibody
    • Transcription factor-like protein MRGX antibody
    see all

Anti-Mortality Factor 4 like 2 antibody images

  • Anti-Mortality Factor 4 like 2 antibody (ab49184) at 0.2 µg/ml + Fetal brain lysate at 10 µg with 5% skim milk in PBS.

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 32 kDa
    Observed band size : 32 kDa
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human brain tissue labelling Mortality Factor 4 like 2 with ab49184 at 4-8µg/ml. Arrows indicate positvely labelled neural cells. Magnification: x400.

References for Anti-Mortality Factor 4 like 2 antibody (ab49184)

ab49184 has not yet been referenced specifically in any publications.

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