Anti-Mortality Factor 4 like 2 antibody (ab66507)


  • Product nameAnti-Mortality Factor 4 like 2 antibody
    See all Mortality Factor 4 like 2 primary antibodies
  • Description
    Rabbit polyclonal to Mortality Factor 4 like 2
  • Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Saccharomyces cerevisiae, Chimpanzee
  • Immunogen

    A region within synthetic peptide: MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN, corresponding to N terminal amino acids 1-50 of Human Mortality Factor 4 like 2

  • Positive control
    • WB: HepG2 cell lysate IHC-P: Human kidney tissue


Our Abpromise guarantee covers the use of ab66507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 32 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/312500.


  • FunctionComponent of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
  • Sequence similaritiesBelongs to the MRG family.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0026 antibody
    • MO4L2_HUMAN antibody
    • MORF related gene X protein antibody
    • MORF-related gene X protein antibody
    • Morf4l2 antibody
    • MORFL2 antibody
    • Mortality factor 4 like protein 2 antibody
    • Mortality factor 4-like protein 2 antibody
    • MRGX antibody
    • MSL3 2 protein antibody
    • Protein MSL3-2 antibody
    • Transcription factor like protein MRGX antibody
    • Transcription factor-like protein MRGX antibody
    see all

Anti-Mortality Factor 4 like 2 antibody images

  • Anti-Mortality Factor 4 like 2 antibody (ab66507) at 1.25 µg/ml + HepG2 cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 32 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling Mortality Factor 4 like 2 with ab66507 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubule. Magnification: 400X.

References for Anti-Mortality Factor 4 like 2 antibody (ab66507)

ab66507 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for providing details.

The protocol is fine however there is one step that I would change before trying replacement vial or antibody. In our own lab we test antibodies on 100C, 10 minutes boiled samples. I would encourage y...

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Thank you for your email. I am sorry to hear that you have been experiencing problems with this antibody.

I have read the details you have kindly provided and have following further questions for better understanding of the problem;


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