Mouse Alpha B Crystallin full length protein (ab94437)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesMouse
    • SequenceMDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFST ATSLSPFYLR PPSFLRAPSW IDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVA AAPKK
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab94437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % by SDS-PAGE.
    Purified by proprietary chromatographic techniques. <95% as determined by SDS-PAGE and RP-HPLC.
  • FormLiquid
  • Additional NotesFor long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris buffered saline, pH 8.0

General info

  • Alternative names
    • AACRYA
    • Alpha B crystallin
    • Alpha crystallin B chain
    • Alpha(B)-crystallin
    • Alpha-crystallin B chain
    • CRYA2
    • CRYAB
    • CRYAB_HUMAN
    • Crystallin alpha B
    • Crystallin alpha polypeptide 2
    • CTPP2
    • Heat shock 20 kD like protein
    • Heat shock protein beta 5
    • Heat shock protein beta-5
    • HSPB5
    • Renal carcinoma antigen NY REN 27
    • Renal carcinoma antigen NY-REN-27
    • Rosenthal fiber component
    see all
  • FunctionMay contribute to the transparency and refractive index of the lens.
  • Tissue specificityLens as well as other tissues.
  • Involvement in diseaseDefects in CRYAB are the cause of myofibrillar alpha-B crystallin-related (MFM-CRYAB) [MIM:608810]. A neuromuscular disorder that results in weakness of the proximal and distal limb muscles, weakness of the neck, velopharynx and trunk muscles, hypetrophic cardiomyopathy, and cataract in a subset of patients.
  • Sequence similaritiesBelongs to the small heat shock protein (HSP20) family.
  • Cellular localizationCytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • Target information above from: UniProt accession P02511 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Mouse Alpha B Crystallin full length protein (ab94437)

ab94437 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94437.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"