Mouse Angiopoietin 2 peptide (ab9077)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesMouse
    • SequenceNFRKSVDS TGRRQYQVQN GP (mouse)
    • Amino acids21 to 40

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9077 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.02% sodium azide

General Info

  • Alternative names
    • AGPT 2
    • Agpt2
    • ANG 2
    • ANG-2
    • ANG2
    • Angiopoietin 2a
    • Angiopoietin 2B
    • Angiopoietin-2
    • Angiopoietin2
    • ANGP2_HUMAN
    • ANGPT 2
    • Angpt2
    • Tie2 ligand
    see all
  • FunctionCan induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
  • Sequence similaritiesContains 1 fibrinogen C-terminal domain.
  • DomainThe Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Mouse Angiopoietin 2 peptide (ab9077)

ab9077 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I have checked with the lab and unfortunately they are not able to do custom peptide synthesis. Sorry we could not be more helpful in this instance. Please let me know if you have any further questions.

Thank you for your enquiry. Ab9077 - Angiopoietin 2 peptide - is the Immunizing Peptide for Angiopoietin 2 antibody, ab8452. The peptide has actually not been tested in blocking, and that application has recently been removed from the datasheet. Howeve...

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No, this is not suitable for western blotting due to the small size of the peptide. This is the immunising peptide and can be used for blocking in western blotting.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"