Overview

  • Product name
    Mouse AP3B2 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Mouse
    • Sequence
      LLEENA/PEKAFYGSEE
    • Amino acids
      260 to 274

Associated products

Specifications

Our Abpromise guarantee covers the use of ab48404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-AP3B2 antibody (ab48269)

    Neutralising

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • Adapter-related protein complex 3 subunit beta-2
    • Adaptor protein complex AP-3 subunit beta-2
    • Adaptor related protein complex 3 beta 2 subunit
    • AP 3 complex subunit beta 2
    • AP-3 complex subunit beta-2
    • AP3B2
    • AP3B2_HUMAN
    • beta NAP
    • Beta-3B-adaptin
    • Beta3b
    • Beta3B adaptin
    • Clathrin assembly protein complex 3 beta 2 large chain
    • Clathrin assembly protein complex 3 beta-2 large chain
    • NAPTB
    • Neuron specific vesicle coat protein and cerebellar degeneration antigen
    • Neuron-specific vesicle coat protein beta-NAP
    • Neuronal adaptin like protein beta subunit
    see all
  • Function
    Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.
  • Tissue specificity
    Expression is specific to nervous system. Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles. Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deeper layers exhibit stronger expression).
  • Sequence similarities
    Belongs to the adaptor complexes large subunit family.
  • Developmental stage
    Expressed from early in development through adulthood.
  • Cellular localization
    Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Golgi apparatus. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • Information by UniProt

References

ab48404 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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