Mouse Bile Acid Receptor NR1H4 peptide (ab39820)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesMouse
    • SequenceRKNVKQHADQTVNED
    • Amino acids244 to 238

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Bile Acid Receptor NR1H4 antibody (ab28480)

    Neutralising

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • BAR
    • Bile acid receptor
    • Farnesoid X activated receptor
    • Farnesoid X receptor
    • Farnesoid X-activated receptor
    • Farnesol receptor HRR 1
    • Farnesol receptor HRR-1
    • Farnesol receptor HRR1
    • FXR
    • HRR 1
    • HRR1
    • NR1H4
    • NR1H4_HUMAN
    • Nuclear receptor subfamily 1 group H member 4
    • Retinoid X receptor interacting protein 14
    • Retinoid X receptor-interacting protein 14
    • RIP 14
    • RIP14
    • RXR interacting protein 14
    • RXR-interacting protein 14
    see all
  • FunctionLigand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
  • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Mouse Bile Acid Receptor NR1H4 peptide (ab39820)

ab39820 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab39820.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"