Overview

Description

  • Nature
    Synthetic

Specifications

Our Abpromise guarantee covers the use of ab30867 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Brain specific homeobox/POU domain protein 3A
    • Brain-3A
    • Brain-specific homeobox/POU domain protein 3A
    • Brn 3.0
    • BRN 3A
    • Brn-3A
    • Brn3
    • BRN3A
    • class 4
    • FLJ13449
    • Homeobox/POU domain protein RDC 1
    • Homeobox/POU domain protein RDC-1
    • Homeobox/POU domain protein RDC1
    • Oct T1
    • Oct-T1
    • OctT1
    • PO4F1_HUMAN
    • POU class 4 homeobox 1
    • POU domain
    • POU Domain Class 4 Transcription Factor 1
    • Pou4f1
    • RDC 1
    • RDC1
    • transcription factor 1
    see all
  • Function
    Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.
  • Tissue specificity
    Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye.
  • Sequence similarities
    Belongs to the POU transcription factor family. Class-4 subfamily.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 POU-specific domain.
  • Developmental stage
    Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab30867 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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