Overview

Description

  • Nature
    Synthetic

Specifications

Our Abpromise guarantee covers the use of ab60452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Purity
    70 - 90% by HPLC.

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • avian-type
    • CAB27
    • CALB
    • CALB 1
    • CALB1
    • CALB1_HUMAN
    • Calbindin
    • Calbindin 1 28kDa
    • Calbindin D28
    • D 28K
    • D-28K
    • D28K
    • OTTHUMP00000166027
    • OTTHUMP00000225441
    • RTVL H protein
    • Vitamin D dependent calcium binding protein
    • Vitamin D dependent calcium binding protein avian type
    • Vitamin D-dependent calcium-binding protein
    see all
  • Function
    Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
  • Sequence similarities
    Belongs to the calbindin family.
    Contains 5 EF-hand domains.
  • Domain
    This protein has four functional calcium-binding sites; potential sites II and VI have lost affinity for calcium.
  • Information by UniProt

References

This product has been referenced in:
  • Kooijmans RN  et al. Inhibitory interneuron classes express complementary AMPA-receptor patterns in macaque primary visual cortex. J Neurosci 34:6303-15 (2014). Read more (PubMed: 24790201) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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