Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Accession
    • Species
      Mouse
    • Sequence
      CTPSSPSESKRKVEDDE
    • Amino acids
      100 to 116

Associated products

Specifications

Our Abpromise guarantee covers the use of ab8374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • CASP 12
    • CASP-12
    • Casp12
    • CASP12P1
    • caspase 12 (gene/pseudogene)
    • caspase 12 pseudogene 1
    • CASPC_HUMAN
    • Inactive caspase-12
    • OTTHUMP00000207032
    see all
  • Function
    Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.
  • Tissue specificity
    Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis.
  • Sequence similarities
    Belongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • Information by UniProt

References

ab8374 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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