The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesThis product is primarily designed for use as a blocking peptide for ab80, Rabbit polyclonal to mouse p19ARF.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
Cyclin dependent kinase inhibitor 2A
RelevanceThe gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons. Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A, isoform 2 and isoform 3 a.k.a p12), two of which are known to function as inhibitors of CDK4 kinase. One other transcript that is generated from this gene contains an alternate reading frame (ARF), with the first exon located 20kb upstream of the remainder of the gene(isoform 4 a.k.a. p14ARF, p19ARF, ARF). In spite of the structural and some functional differences, all the proteins encoded by the CDKN2A gene are involved in cell cycle G1 control.
References for Mouse CDKN2A/p19ARF peptide (ab2659)
This product has been referenced in:
Chidlow G et al. Ocular Expression and Distribution of Products of the POAG-Associated Chromosome 9p21 Gene Region. PLoS One8:e75067 (2013).
Read more (PubMed: 24069379) »