Overview

  • Product name
    Mouse CEBP Beta peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Mouse
    • Sequence
      MHRLLAWDAACLPPPAAFPKLH
    • Amino acids
      1 to 21

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CEBP Beta antibody [18F8] (ab15049)

    Neutralising

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • AGP/EBP
    • C EBP beta
    • C/EBP beta
    • C/EBP related protein 2
    • CCAAT Enhancer Binding Protein beta
    • CCAAT/enhancer-binding protein beta
    • CEBPB
    • CEBPB_HUMAN
    • CRP2
    • IL 6DBP
    • IL6DBP
    • Interleukin 6 dependent binding protein
    • LAP
    • Liver activator protein
    • Liver enriched transcriptional activator
    • NF IL6
    • NFIL6
    • Nuclear factor NF IL6
    • Nuclear factor NF-IL6
    • SF B
    • SFB
    • Silencer factor B
    • TCF-5
    • TCF5
    • Transcription factor 5
    see all
  • Function
    Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation.
  • Tissue specificity
    Expressed at low levels in the lung, kidney and spleen.
  • Sequence similarities
    Belongs to the bZIP family. C/EBP subfamily.
    Contains 1 bZIP domain.
  • Domain
    the 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
  • Post-translational
    modifications
    Sumoylated by polymeric chains of SUMO2 or SUMO3.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab39810 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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