Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab74382 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • ADGRE1
    • Adhesion G protein coupled receptor E1
    • Adhesion G protein-coupled receptor E1
    • AGRE1_HUMAN
    • Cell surface glycoprotein EMR1
    • Cell surface glycoprotein F4/80
    • DD7A5 7
    • Egf like module containing mucin like hormone receptor like 1
    • Egf like module containing mucin like hormone receptor like sequence 1
    • EGF like module receptor 1
    • EGF TM7
    • EGF-like module receptor 1
    • EGF-like module-containing mucin-like hormone receptor-like 1
    • EGFTM7
    • EMR 1
    • EMR1 hormone receptor
    • Gpf480
    • Ly71
    • Lymphocyte antigen 71
    • TM7LN3
    see all
  • FunctionOrphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
  • Tissue specificityExpression is restricted to eosinophils.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
    Contains 6 EGF-like domains.
    Contains 1 GPS domain.
  • Cellular localizationCell membrane.
  • Information by UniProt

References for Mouse F4/80 peptide (ab74382)

ab74382 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"