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Amino Acid Sequence
This sequence is highly conserved in rat paxillin and is also found in all three isoforms, alpha, beta and gamma. There is low homology between this sequence and the conserved sequence site in human paxillin (around Serine 85).
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Paxillin (phospho S83) antibody (
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.05% Sodium Azide
Paired box protein Pax 1
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Belongs to the paxillin family.
Contains 4 LIM zinc-binding domains.
Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
Information by UniProt
has not yet been referenced specifically in any publications.
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