Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Accession
    • Species
      Mouse

Specifications

Our Abpromise guarantee covers the use of ab8464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • Receptor interacting protein 3
    • Receptor interacting serine threonine kinase 3
    • Receptor interacting serine/threonine protein kinase 3
    • Receptor-interacting protein 3
    • Receptor-interacting serine/threonine-protein kinase 3
    • RIP 3
    • RIP like protein kinase 3
    • RIP-3
    • RIP-like protein kinase 3
    • RIPK 3
    • RIPK3
    • RIPK3_HUMAN
    see all
  • Function
    Promotes apoptosis.
  • Tissue specificity
    Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers.
  • Sequence similarities
    Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • Western blot analysis of RIP3 in 3T3 (Mouse embryonic fibroblast cell line) whole cell lysate in the absence (A) or presence (B) of blocking peptide ab8464 with RIP3 antibody at 1 μg/ml.

References

ab8464 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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