Mouse SDF1 beta full length protein (ab51940)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesMouse
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab51940 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 95 % by SDS-PAGE.
    >98% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.1 ng per µg.
  • FormLyophilised
  • Additional NotesThe reconstituted solution can be diluted into an aqueous buffer and stored at 4°C for 1 week or –20°C for future use.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is <0.1 ng per µg.

  • ReconstitutionCentrifuge the vial prior to opening. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/ml. (The protein may appear as a haze or film, which is difficult to see at the bottom of the vial. )

General info

  • Alternative names
    • Chemokine (C X C motif) ligand 12
    • Chemokine (CXC motif) ligand 12
    • CXCL 12
    • CXCL12
    • hIRH
    • IRH
    • PBSF
    • Pre B cell growth stimulating factor
    • SCYB 12
    • SCYB12
    • SDF 1
    • SDF 1 beta
    • SDF 1a
    • SDF 1b
    • SDF1
    • SDF1a
    • SDF1b
    • Stromal cell derived factor 1
    • Stromal cell derived factor 1 beta
    • TLSF
    • TLSF a
    • TLSF b
    • TLSFa
    • TLSFb
    • TPAR 1
    • TPAR1
    see all
  • RelevanceStromal cell derived factor beta 1 (SDF1) is a 70 amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. This member of the intercrine alpha (chemokine CxC) family is a chemoattractant active on T lymphocytes, monocytes, but not neutrophils. Targeted deletion of SDF1 gene resulted in defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF1 has been shown to be chemotactic for lymphocytes. In addition, SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin) and a co receptor for HIV1 entry into T cells (SDF1 binding to CXCR4 inhibits HIV1 entry).
  • Cellular localizationSecreted

References for Mouse SDF1 beta full length protein (ab51940)

ab51940 has not yet been referenced specifically in any publications.

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