Overview

  • Product nameAnti-MPDU1 antibody
  • Description
    Rabbit polyclonal to MPDU1
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (10-30 aa in length) in the region of 259~272 of MPDU1(Human) conjugated to KLH

  • Positive control
    • Human breast carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab38856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500.
ELISA 1/1000.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionRequired for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.
  • Involvement in diseaseDefects in MPDU1 are the cause of congenital disorder of glycosylation type 1F (CDG1F) [MIM:609180]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • Sequence similaritiesBelongs to the MPDU1 (TC 2.A.43.3) family.
    Contains 2 PQ-loop domains.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CDGIF antibody
    • LEC35 antibody
    • mannose P dolichol utilization defect 1 antibody
    • Mannose-P-dolichol utilization defect 1 protein antibody
    • MPDU1 antibody
    • MPU1_HUMAN antibody
    • PQLC5 antibody
    • SL15 antibody
    • Suppressor of Lec15 and Lec35 glycosylation mutation homolog antibody
    see all

Anti-MPDU1 antibody images

  • Ab38856 at 1/50 dilution staining human breast carcinoma; a peroxidase-conjugated secondary antibody, followed by AEC staining was used.
  • Anti-MPDU1 antibody (ab38856)ab38856 used at a dilution of 1:100 - 1:500

References for Anti-MPDU1 antibody (ab38856)

ab38856 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"