Overview

  • Product nameAnti-MPRIP antibody
    See all MPRIP primary antibodies
  • Description
    Rabbit polyclonal to MPRIP
  • Specificityab111381 detects endogenous levels of total MPRIP protein.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from an internal region of Human MPRIP.

  • Positive control
    • Human lymph node tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab111381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionTargets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
  • Sequence similaritiesContains 2 PH domains.
  • Cellular localizationCytoplasm > cytoskeleton. Colocalizes with F-actin.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9530046C02 antibody
    • AA536749 antibody
    • AI647711 antibody
    • C76423 antibody
    • KIAA0864 antibody
    • M-RIP antibody
    • MGC67316 antibody
    • mKIAA0864 antibody
    • Mprip antibody
    • MPRIP_HUMAN antibody
    • Myosin phosphatase Rho-interacting protein antibody
    • p116 Rho-interacting protein antibody
    • p116Rip antibody
    • Rho-interacting protein 3 antibody
    • Rhoip3 antibody
    • RIP3 antibody
    • RP23-180B18.4 antibody
    see all

Anti-MPRIP antibody images

  • ab111381 at 1/50 dilution staining MPRIP in paraffin-embedded Human Lymph tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

References for Anti-MPRIP antibody (ab111381)

ab111381 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"