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ab214 has been referenced in 32 publications.

  • Ward TA  et al. Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes. PLoS One 12:e0179278 (2017). WB ; Human . PubMed: 28628639
  • Petroni M  et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ 23:197-206 (2016). WB ; Human . PubMed: 26068589
  • Palermo V  et al. CDK1 phosphorylates WRN at collapsed replication forks. Nat Commun 7:12880 (2016). WB . PubMed: 27634057
  • Clynes D  et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun 6:7538 (2015). IP, ICC/IF ; Human . PubMed: 26143912
  • Chen WT  et al. ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion. Elife 4:N/A (2015). WB ; Human . PubMed: 26030852
  • Becker A  et al. ATM alters the otherwise robust chromatin mobility at sites of DNA double-strand breaks (DSBs) in human cells. PLoS One 9:e92640 (2014). WB, IF ; Human . PubMed: 24651490
  • Clynes D  et al. ATRX dysfunction induces replication defects in primary mouse cells. PLoS One 9:e92915 (2014). WB, IF ; Mouse . PubMed: 24651726
  • Pang B  et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun 4:1908 (2013). WB ; Human . PubMed: 23715267
  • Zhang ZZ  et al. Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. World J Gastroenterol 19:1968-74 (2013). IHC-P ; Human . PubMed: 23569343
  • Birkenkamp-Demtröder K  et al. Keratin23 (KRT23) Knockdown Decreases Proliferation and Affects the DNA Damage Response of Colon Cancer Cells. PLoS One 8:e73593 (2013). WB ; Human . PubMed: 24039993
  • Quennet V  et al. CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1. Nucleic Acids Res 39:2144-52 (2011). WB ; Human . PubMed: 21087997
  • Choudhury A  et al. MRE11 Expression Is Predictive of Cause-Specific Survival following Radical Radiotherapy for Muscle-Invasive Bladder Cancer. Cancer Res 70:7017-7026 (2010). IHC-P ; Human . PubMed: 20843819
  • Kadaja M  et al. Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses. PLoS Pathog 5:e1000397 (2009). ICC/IF ; Human . PubMed: 19390600
  • Stagno D'Alcontres M  et al. Lack of TRF2 in ALT cells causes PML-dependent p53 activation and loss of telomeric DNA. J Cell Biol 179:855-67 (2007). ICC/IF ; Human . PubMed: 18056407
  • Buck D  et al. Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly. Cell 124:287-99 (2006). PubMed: 16439204
  • Giannini G  et al. Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. Oncogene 23:2640-7 (2004). PubMed: 15048091
  • Robison JG  et al. Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks. J Biol Chem 279:34802-10 (2004). PubMed: 15180989
  • Wilkinson DE & Weller SK Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response. J Virol 78:4783-96 (2004). PubMed: 15078960
  • Xu X & Stern DF NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J Biol Chem 278:8795-803 (2003). PubMed: 12499369
  • Lee JH  et al. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Mol Cancer Res 1:674-81 (2003). PubMed: 12861053
  • Franchitto A  et al. The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase. Oncogene 22:2110-20 (2003). PubMed: 12687013
  • Stewart GS  et al. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 421:961-6 (2003). PubMed: 12607005
  • Celeste A  et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol 5:675-9 (2003). PubMed: 12792649
  • Xu X & Stern DF NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. FASEB J 17:1842-8 (2003). PubMed: 14519663
  • Uziel T  et al. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J 22:5612-21 (2003). PubMed: 14532133
  • Lukas C  et al. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat Cell Biol 5:255-60 (2003). PubMed: 12598907
  • Stracker TH  et al. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418:348-52 (2002). PubMed: 12124628
  • Nakanishi K  et al. Interaction of FANCD2 and NBS1 in the DNA damage response. Nat Cell Biol 4:913-20 (2002). PubMed: 12447395
  • Limoli CL  et al. UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization. Proc Natl Acad Sci U S A 99:233-8 (2002). PubMed: 11756691
  • Lombard DB & Guarente L Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res 60:2331-4 (2000). PubMed: 10811102
  • Wang Y  et al. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 14:927-39 (2000). PubMed: 10783165
  • Gatei M  et al. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat Genet 25:115-9 (2000). PubMed: 10802669


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