Anti-MRP1 antibody (ab81903)

Overview

  • Product nameAnti-MRP1 antibody
    See all MRP1 primary antibodies
  • Description
    Goat polyclonal to MRP1
  • Specificityab81903 is expected to recognize all reported isoforms (NP_004987.2; NP_063915.2; NP_063953.2; NP_063954.2; NP_063955.2).
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Cow, Dog, Cynomolgus Monkey
  • Immunogen

    Synthetic peptide:

    C-HQSDLKVDENQKAYY

    , corresponding to internal sequence amino acids 1176-1190 of Human MRP1 (NP_004987.2).

  • Positive control
    • A549 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab81903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.05 - 0.2 µg/ml. Detects a band of approximately 150 kDa (predicted molecular weight: 171 kDa).

Target

  • FunctionMediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
  • Tissue specificityLung, testis and peripheral blood mononuclear cells.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABC 29 antibody
    • ABC29 antibody
    • ABCC 1 antibody
    • ABCC antibody
    • Abcc1 antibody
    • ATP binding cassette sub family C (CFTR/MRP) member 1 antibody
    • ATP binding cassette sub-family C member 1 antibody
    • ATP-binding cassette sub-family C member 1 antibody
    • DKFZp686N04233 antibody
    • DKFZp781G125 antibody
    • GS X antibody
    • GSX antibody
    • Leukotriene C(4) transporter antibody
    • LTC4 transporter antibody
    • MRP 1 antibody
    • MRP antibody
    • MRP1_HUMAN antibody
    • Multidrug resistance associated protein 1 antibody
    • Multidrug resistance protein antibody
    • Multidrug resistance-associated protein 1 antibody
    • Multiple drug resistance associated protein antibody
    • Multiple drug resistance protein 1 antibody
    see all

Anti-MRP1 antibody images

References for Anti-MRP1 antibody (ab81903)

ab81903 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 500000 cells
Gel Running Conditions Reduced Denaturing (8%)
Sample Mouse Cell lysate - whole cell (GLUTag entereoendocrine murine cell line)
Specification GLUTag entereoendocrine murine cell line
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: rT°C
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Verified customer

Submitted Feb 05 2015

It is not unknown for an antibody that is predicted to work in species not to end up reacting with that species, that is why we state that is only predicted to react, not guaranteed. The prediction of reactivity is based purely on sequence homology. A...

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Thank you for providing your protocol information. I have looked over the protocol you sent and I have a few more specific questions/suggestions: 1 - Did you use 5%milk or BSA when testing this antibody? Switching to a different block may help. 2 - Wha...

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Could you please send me a copy of the protocol that you are currently using, so that I can look over it and see if can make any suggestions.

Thank you for contacting us. ab3364; anti P Glycoprotein is no longer available in our catalogue. However we have similar products available to buy. The catalogue numbers are ab3083; ab3366; ab10333; ab80594; ab80626. Please check the da...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"