• Product nameAnti-MRP8 antibody
    See all MRP8 primary antibodies
  • Description
    Mouse polyclonal to MRP8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human MRP8 protein (AAH05928).

  • Positive control
    • Human lung cancer tissue lysate; MRP8 transfected 293T cell lysate



Our Abpromise guarantee covers the use of ab88693 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 11 kDa.


  • FunctionCalcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS) (By similarity). Promotes tubulin polymerization. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
  • Tissue specificityExpressed by macrophages in chronic inflammations. Also expressed in epithelial cells constitutively or induced during dermatoses.
  • Sequence similaritiesBelongs to the S-100 family.
    Contains 2 EF-hand domains.
  • Cellular localizationSecreted. Cytoplasm. Cytoplasm > cytoskeleton. Cell membrane. Associates with tubulin filaments in activated monocytes. Targeted to the cell surface upon calcium influx. Released from blood leukocytes upon exposure to CSF2/GM-CSF, bacterial lipopolysaccharide (LPS) and during inflammatory processes. Serum levels are high in patients suffering from chronic inflammation.
  • Information by UniProt
  • Database links
  • Alternative names
    • 60B8Ag antibody
    • AI323541 antibody
    • B8Ag antibody
    • BEE11 antibody
    • CAGA antibody
    • Calgranulin-A antibody
    • Calprotectin L1L subunit antibody
    • Calprotectin, included antibody
    • CFAG antibody
    • CGLA antibody
    • Chemotactic cytokine CP-10 antibody
    • CP-10 antibody
    • Cystic fibrosis antigen antibody
    • L1Ag antibody
    • Leukocyte L1 complex light chain antibody
    • MA387 antibody
    • MIF antibody
    • Migration inhibitory factor-related protein 8 antibody
    • MRP-8 antibody
    • Myeloid-related protein 8 antibody
    • Neutrophil cytosolic 7 kDa protein antibody
    • NIF antibody
    • p8 antibody
    • Pro-inflammatory S100 cytokine antibody
    • Protein S100-A8 antibody
    • S100 calcium binding protein A8 (calgranulin A) antibody
    • S100 calcium binding protein A8 antibody
    • S100 calcium-binding protein A8 antibody
    • S100A8 antibody
    • S100A8/S100A9 complex, included antibody
    • S10A8_HUMAN antibody
    • Urinary stone protein band A antibody
    see all

Anti-MRP8 antibody images

  • Anti-MRP8 antibody (ab88693) at 1 µg/ml + human lung cancer tissue lysate at 50 µg

    Predicted band size : 11 kDa
    Observed band size : 11 kDa
  • All lanes : Anti-MRP8 antibody (ab88693) at 1 µg/ml

    Lane 1 : MRP8 transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 11 kDa
    Observed band size : 11 kDa
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

References for Anti-MRP8 antibody (ab88693)

ab88693 has not yet been referenced specifically in any publications.

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