Anti-MRPL41 antibody (ab121821)

Overview

• Product name
  Anti-MRPL41 antibody
  See all MRPL41 primary antibodies
• Description
  Rabbit polyclonal to MRPL41
• Tested applications
  Suitable for: IHC-P, WB, ICC/IFmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  antigen sequence: KPYVSYLAPE SEETPLTAAQ LFSEAVAPAI EKDFKDGTFD PDNLEKYGFE PTQEGKLFQL YPRNFLR, corresponding to amino acids 71-137 of Human MRPL41.

  Run BLAST with Run BLAST with
• Positive control
  • Human rectum tissue; RT-4 and U-251 MG cell lysates; U-251MG cells

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage buffer
  pH: 7.20
  Preservative: 0.02% Sodium azide
  Constituents: 59% PBS, 40% Glycerol
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Cell Biology
  • Cell Cycle
  • Cell Cycle Inhibitors
  • Cip / Kip

  • Cell Biology
  • Cell Cycle
  • Cell Cycle Inhibitors
  • p53

  • Cell Biology
  • Apoptosis
  • Intracellular
  • p53 Pathway

  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Mitochondria

  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • Translation
  • Ribosome

  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • Translation
  • Mito. Translation

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Cell Cycle Inhibitors
  • Cip/Kip

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Cell Cycle Inhibitors
  • p53

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• Function
  Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.
• Tissue specificity
  Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level).
• Sequence similarities
  Belongs to the ribosomal protein L41 family.
• Cellular localization
  Mitochondrion.

• Target information above from: UniProt accession Q8IXM3 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 64975 Human
  • Omim: 611846 Human
  • SwissProt: Q8IXM3 Human
  • Unigene: 44017 Human
• Alternative names
  • 39S ribosomal protein L27 homolog antibody
  • 39S ribosomal protein L41 antibody
  • 39S ribosomal protein L41 mitochondrial antibody

  • Bcl-2-interacting mitochondrial ribosomal protein L41 antibody
  • BMRP antibody
  • Cell proliferation-inducing gene 3 protein antibody
  • L41mt antibody
  • mitochondrial antibody
  • Mitochondrial ribosomal protein L41 antibody
  • MRP L27 antibody
  • MRP-L27 homolog antibody
  • MRP-L41 antibody
  • MRPL27 antibody
  • mRpL41 antibody
  • PIG3 antibody
  • Proliferation inducing gene 3 antibody
  • RM41_HUMAN antibody
  • RPML27 antibody

  see all

Protocols

• Immunohistochemistry protocols
• Immunocytochemistry & immunofluorescence protocols
• Western blot protocols