RelevanceMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternate splice variants of this gene have been described but their full length nature has not been determined.
All lanes : Anti-MRPS34 antibody (ab74104) at 1/500 dilution
Lane 1 : extracts from HeLa cells Lane 2 : extracts from HUVEC cells Lane 3 : extracts from HT-29 cells Lane 4 : extracts from A549 cells Lane 5 : extracts from Jurkat cells Lane 6 : extracts from HeLa cells with immunizing peptide at 10 µg
Lysates/proteins at 20 µg per lane.
Predicted band size : 26 kDa Observed band size : 26 kDa
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