Overview

  • Product name
  • Description
    Rabbit polyclonal to MSC
  • Specificity
    Detects endogenous levels of total MSC protein.
  • Tested applications
    Suitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide from internal of human Musculin.

  • Positive control
    • Human lymph node tissue and Jurkat cell extract

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab64954 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
IHC-P 1/50 - 1/100.
ELISA 1/10000.

Target

  • Function
    Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.
  • Tissue specificity
    Expressed in lymphoid tissues, B-cell lines and activated B-cells.
  • Sequence similarities
    Contains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABF-1 antibody
    • ABF1 antibody
    • Activated B cell factor 1 antibody
    • Activated B-cell factor 1 antibody
    • bHLHa22 antibody
    • Class A basic helix-loop-helix protein 22 antibody
    • Msc antibody
    • MUSC_HUMAN antibody
    • Musculin antibody
    • MYOR antibody
    see all

Anti-MSC antibody images

  • All lanes : Anti-MSC antibody (ab64954) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Jurkat cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 22 kDa
    Observed band size : 22 kDa
  • Immunohistochemical analysis of paraffin-embedded human lymph node tissue using ab64954 at 1/50-1/100 dilution. The right hand panel was also treated with the immunising peptide.

References for Anti-MSC antibody (ab64954)

ab64954 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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