Overview

  • Product name
  • Description
    Rabbit polyclonal to MSI2
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Guinea pig, Ferret, Lizard, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 250-300 of Human MSI2 (NP_620412.1).

  • Positive control
    • HeLa whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab114107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
    • Tissue specificity
      Ubiquitous; detected at low levels.
    • Involvement in disease
      Note=Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).
    • Sequence similarities
      Belongs to the Musashi family.
      Contains 2 RRM (RNA recognition motif) domains.
    • Post-translational
      modifications
      Phosphorylated.
    • Cellular localization
      Cytoplasm. Associated with polysomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ36569 antibody
      • MGC3245 antibody
      • Msi2 antibody
      • MSI2/HOXA9 fusion gene, included antibody
      • MSI2H antibody
      • MSI2H_HUMAN antibody
      • Musashi 2 antibody
      • Musashi homolog 2 antibody
      • Musashi RNA binding protein 2 antibody
      • Musashi, Drosophila, homolog of, 2 antibody
      • Musashi-2 antibody
      • RNA binding protein Musashi homolog 2 antibody
      • RNA-binding protein Musashi homolog 2 antibody
      • WD 40 repeat protein MSI2 antibody
      see all

    Images

    • Detection of Human MSI2 by Western blot of Immunoprecipitate.
      MSI2 was immunoprecipitated from HeLa whole cell lysate, using ab114107 at 6 µg/mg lysate (1 mg for IP, 20% of IP loaded). ab114107 was used for the subsequent WB at 1 µg/ml.
      Detection: Chemiluminescence with an exposure time of 30 seconds.

    References

    ab114107 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab114107.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up