Overview

  • Product name
  • Description
    Rabbit polyclonal to MSL1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen: FGSTERKTPV KKLAPEFSKV KTKTPKHSPI KEEPCGSLSE TVCKRELRSQ ETPEKPRSSV DTPPRLSTPQ KGPSTHPKEK AFSSEIEDLP YLSTTEMY, corresponding to amino acids 335-432 of Human MSL1v1 (Q68DK7).

  • Positive control
    • Human cerebellum tissue, A431 cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. The following steps are recommended prior to antibody incubation: cells fixation in ice cold 4% paraformaldehyde pH 7.2-7.3, followed by permeabilization with 0.1% Triton X-100 in PBS for 3x5 minutes.

Target

  • Function
    Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure.
  • Sequence similarities
    Belongs to the msl-1 family.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • hMSL1 antibody
    • male specific lethal 1 antibody
    • male specific lethal 1 homolog 1 antibody
    • male specific lethal 1 homolog antibody
    • male specific lethal 1 like 1 antibody
    • Male-specific lethal 1 homolog antibody
    • Male-specific lethal 1-like 1 antibody
    • Male-specific lethal-1 homolog 1 antibody
    • MSL 1 antibody
    • MSL-1 antibody
    • Msl1 antibody
    • MSL1 like 1 antibody
    • MSL1-like 1 antibody
    • MSL1_HUMAN antibody
    see all

Images

  • ab121762 at 1/100 dilution staining MSL1v1 in Paraffin-emebedded Human cerebellum tissue by Immunohistochemistry.
  • Immunofluorescent staining of Human cell line A431 using ab121762 at a concentration of 4 µg/ml. Note: positivity in nucleus but not nucleoli (green).

References

ab121762 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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