Overview

  • Product nameAnti-MT3 antibody
    See all MT3 primary antibodies
  • Description
    Mouse monoclonal to MT3
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human, Chimpanzee, Macaque Monkey
  • Immunogen

    GST-tagged recombinant full length protein: MDPETCPCPS GGSCTCADSC KCEGCKCTSC KKSCCSCCPA ECEKCAKDCV, corresponding to amino acids 1-68 of Human MT3

Properties

Applications

Our Abpromise guarantee covers the use of ab76618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 7 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionBinds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
  • Tissue specificityAbundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain.
  • Sequence similaritiesBelongs to the metallothionein superfamily. Type 1 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • GIF antibody
    • GIFB antibody
    • GRIF antibody
    • Growth inhibitory factor antibody
    • Metallothionein 3 (growth inhibitory factor (neurotrophic)) antibody
    • Metallothionein 3 antibody
    • Metallothionein III antibody
    • Metallothionein-3 antibody
    • Metallothionein-III antibody
    • Mt 3 antibody
    • MT III antibody
    • MT-3 antibody
    • MT-III antibody
    • MT3 antibody
    • MT3_HUMAN antibody
    • ZnMT3 antibody
    see all

Anti-MT3 antibody images

References for Anti-MT3 antibody (ab76618)

This product has been referenced in:
  • Tao YF  et al. Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation. J Transl Med 12:182 (2014). WB ; Human . Read more (PubMed: 24962166) »

See 1 Publication for this product

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The concentration for ab76618 lot GR60074-1 (1171184) is 0.757mg/ml.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"